EB-meeting - closed meeting

NCOH Annual Scientific Meeting 2018

Welcome
Prof. Marion Koopmans
Head department of Virology, Erasmus MC
Scientific Director Emerging Infectious Diseases Preparedness NCOH

• Emerging Infectious Diseases Preparedness
• Smart and Healthy Farming
• Healthy Wildlife and Ecosystems
• Tackling Antimicrobial Resistance

Emerging Infectious Diseases Preparedness

Updates on the theme Emerging Infectious Diseases
Prof. Marion Koopmans
Head department of Virology, Erasmus MC
Scientific Director Emerging Infectious Diseases Preparedness NCOH

Microencephaly in fetal piglets following in utero inoculation of Zika virus
Dr. Paul Wichgers Schreur, WUR

Extra-respiratory infections with zoonotic and pandemic influenza viruses
Dr. Debby van Riel, Erasmus MC 

Inhibition of chikungunya virus replication by novel nucleoside analogues that target the viral capping enzyme nsP1
Dr. Martijn J. van Hemert, LUMC

Unravelling homo- and heterotypic antibody responses to influenza viruses
Dr. Brenda Westerhuis, Erasmus MC

Broad receptor engagement by an emerging coronavirus
Dr. Wentao Li, UU

Tackling Antimicrobial Resistance

Updates on the theme Tackling Antimicrobial Resistance
Prof. Marc Bonten, Utrecht University Medical Center
Scientific Director Tackling Antimicrobial Resistance NCOH

Volatile compounds as antibiotics
Mariana Avalos Garcia, UL

Antibiotic resistance in the aquatic environment
Dr. Heike Schmitt, RIVM

ESBL prevalence and vegetarian diet
Anouk Meijs, RIVM

An open database for bacterial antimicrobial susceptibility   data associated with whole bacterial genomes
Dr. Sebastien Matamoros, AMC

Epistatic interactions across the genome involving complex biological pathways have contributed to the adaptive evolution of multidrug resistant E. faecium
Dr. Janetta Top, UMCU

Smart and Healthy Farming

Updates on the theme Smart and Healthy Farming
Dr. Annemarie Rebel, Wageningen University and Research
Scientific Director Smart and Healthy Farming NCOH

Stimulating the chicken innate immune system to improve immune fitness
Dr. Christine Jansen, UU

The environmental benefits of plant-based diets challenged
Ir. Martine Hoogsteen, RIVM

Maternal interventions affect piglet intestinal development and immune competence
Dr. Astrid de Greeff, WUR

Associations between the fecal resistome and antimicrobial usage in broilers
Roosmarijn Luiken, UU

Healthy Wildlife and Ecosystems

Updates on the theme Healthy Wildlife and Ecosystems
Prof. Andrea Gröne, Utrecht University
Scientific Director Healthy Wildlife and Ecosystems NCOH

Environmental and social factors promote Lyme disease and Q-fever over various spatio-temporal scales
Dr. Ronald Petie, Wageningen Bioveterinary Research, WUR

Soluble and volatile antimicrobial compounds produced in terrestrial environment
Dr. Paolina Garbeva, NIOO

The ecology of diseases: from cells to ecosystems
Dr. Dedmer van de Waal, NIOO

Water and health: complex interactions and integrated solutions
Dr. Eline Boelee, Deltares
Dr. Harm Duel, Deltares

Selected post doc and PhD talks - YOUNG NCOH

Moderator: Prof. dr. ir. Dick Heederik
Chairman of the Executive Board of the NCOH
Institute of Risk Assessment Sciences
University of Utrecht

AMR

1. The mode of action of of ab-defensins: promising drugs with a high robustness to AMR development
   Shehrazade Jekhmane, UU
    
2. Collateral sensitivity and collateral resistance networks of antibiotic-resistant Streptococcus pneumoniae
   Apostolos Liakopoulos, Leiden University
    
3. Zooming into the pharmacological relevant state: Truly native structural studies of antibiotics-receptor interactions in bacterial cell membranes
   Joao Medeiros-Silva, UU
    
4. Regulatory and mutational analysis of the biosynthetic gene cluster for lugdunomycin, a novel antibiotic with unprecedented chemical structure
   Helga van der Heul, Leiden

Viral entry

1. The 2nd sialic acid-binding site that is lost in human pandemic influenza A viruses contributes to virion binding to and self-elution from receptors
   Wenjuan Du, UU
    
2. Host factors driving pathogenesis: viral protein attachment to tissues                                              
   Nika Nemanichvili, UU
    
3. Identification of sialic acid binding function for the Middle-East respiratory syndrome coronavirus spike glycoprotein
   Wentao Li, UU
    
4. MERS-CoV receptor and attachment factor expression in different animal species
   Widagdo, EMC

Microbial detection

1. Why Midges Matter: the microbiome of midges                                                                           
   Tim Mohlmann PhD, WUR
    
2. Clostridium difficile and the microbiome
   Romy Zwittink PhD, LUMC
    
3. Zoonotic viruses along the market chain
   Reina Sikkema, Erasmus MC
    
4. Quantitative risk assessment of Toxoplasma gondii infection
   Huifang Deng, RIVM
    
5. Virus classification from next generation sequencing data using deep learning                         
   David Nieuwenhuijse, Erasmus MC
    
6. Mlplasmids: a user-friendly tool to predict plasmid- and chromosome- derived sequences for single species
   Sergio Arredondo Alonso, UMC Utrecht

Pathogenesis

1. The role of preexisting flavivirus antibodies in Zika virus infection
   Thomas Langerak, Erasmus MC
    
2. Pathogenesis of Rift Valley Fever in pregnant ewes                                                                    
   Judith Oymans, WUR
    
3. Monitoring, characterization and pathogenesis of Dutch ranaviruses                                       
   Bernardo Saucedo Garnica, UU
    
4. Networking with the enemy
   Dr Alena Gsell, postdoc, Aquatic Ecology, NIOO-KNAW                                                                                                         

Global eradication of measles: are we generating a human niche for animal morbilliviruses?