Registration & coffee at Villa Jongerius

Opening by Merlijn van Rijswijk, Director Netherlands Metabolomics Centre

Keynote speaker Johan Swinnen, Leuven University

Session chair: Celia Berkers, Utrecht University - boardmember NMC

Lipidomic Approaches To Identify Exploitable Vulnerabilities For Cancer Treatment

Single cell metabolomics, new instrumentation, metabolite identification

Session chair: Celia Berkers, Utrecht University 

Rob Vreeken, Maastricht University

Mass Spec Imaging en Metabolomics: Opportunities and Challenges 

Presentation 1: Alida Kindt, Leiden University

Single-cell Untargeted Metabolomics in R (SUM-R)

Presentation 2: Heather Clare Chassaing - Sciex

Using EIEIO as a novel fragmentation technique for complete lipid characterization in a complex matrix

Coffee break

Fluxomics & lipidomics

Session chair: Jildau Bouwman - TNO 

Bert Wouters, Leiden University

Automated segmented-flow analysis – NMR with a novel fluoropolymer flow cell for high-throughput screening

Presentation 1: Esther Zaal - Utrecht University

Rewiring of energy metabolism drives resistance to the proteasome inhibitor bortezomib

Presentation 2: Michel van Weeghel, Amsterdam UMC

4D-lipidomics profiling in adrenoleukodystrophy using vacuum insulated probe heated ESI and trapped ion mobility time-of-flight mass spectrometry

Poster pitches

Session chair: Jildau Bouwman - TNO

Poster pitch 1: Brenda Ammerlaan, DSM

The flavor library: Connecting flavor characteristics to analytical data to help data interpretation in Sensomics

Poster pitch 2: Sandra Pous Torres, DSM

LC-HR-MS profiling methods to unravel the complexity of flavor in food matrices

Poster pitch 3: Vera Plekhova, Ghent University

Electrospun Nanofibrous Samplers (MetaSAMP®) Provide Superior Biofluid Metabolome Stability and Coverage following Direct Laser-Assisted Rapid Evaporative Ionization Mass Spectrometry

Poster pitch 4: Robin Joshi, CSIR-Institute of Himalayan Bioresource Technology

Ion-mobility mass spectrometry: Modern validation approach towards targeted and non-targeted metabolomics method development

Lunch break, posters, stands

Food & Nutrition and microbial applications

Session chair: Justin van der Hooft, Wageningen University

Lars Ove Dragsted, Copenhagen University

Applying metabolomics to study food and dietary intakes and their effects in humans.

Presentatie 1: Sofia Moco

NAD+ - an old cofactor with new tricks

Presentatie 2: Doris Jacobs 

In vivo stable isotope metabolomics to determine the postprandial metabolic fluxes of carbohydrates.

Plant metabolomics

Session chair: Sandrien Desmet, University of Ghent

Harro Bouwmeester, University of Amsterdam

The use of metabolomics to unravel signalling relations with other organisms in the rhizosphere of plants

Presentation 1: Mitja M. Zdouc, Wageningen University

FERMO: Formulation of mEtrics from Reproducible Metabolomics Objects

Presentation 2: Eirini Pegiou, Wageningen University

Metabolomics Reveals Heterogeneity in the Chemical Composition of Green and White Spears of Asparagus (A. officinalis)

Coffee break

Biomedical applications 

Session chair: Michel van Weeghel - Amsterdam UMC

Presentatie 1: Andrea Jáñez Pedrayes, KU Leuven

Study and treatment of congenital disorders of glycosylation based on tracer metabolomics: SLC35A2-CDG

Presentation 2: Rita Simões-Faria - Leuven University

Shear Stress Triggers Metabolic Changes of Endothelial Cells

Presentation 3: Ellen De Paepe, Ghent University

Metabolome Alterations in a Mouse Model Support Microbiome-Metabolite Interactions in a Cohort of Children With Cow’s Milk Allergy

Keynote speaker 

Adriana Carvalho de Souza, DSM

Session chair: Michel van Weeghel  boardmember NMC

Bringing gap flavor for meat alternatives based on insight created by metabolomics.

YoungNMC Presentation and Drinks

Conference dinner at Villa Jongerius

Registration & coffee at Jaarbeurs Utrecht

Opening by moderator Anya Sitaram: brief interview with Roel Vermeulen, University Utrecht and Thomas Hankemeier - Scientific Director NMC

Keynotespeaker Emma Schymanski, University of Luxembourg

Introduction Emma Schymanski by Anya Sitaram

FAIR and Open Science for Metabolomics and Exposomics Identification Efforts

Coffee break and changue of venue

Artificial Intelligence and Biostatistics

Session chair: Justin van der Hooft boardmember NMC

Kris Laukens, University of Antwerp

Artificial Intelligence: engine to make omics clinically actionable?

Presentation 1: Balazs Erdos

Analysing multivariate metabolomics data with complex temporal dynamics from challenge tests using RM-ASCA+

Presentation 2: Daniele Bizzarri

1H-NMR metabolomics-based models to impute common clinical variables and endpoints in epidemiological

studies

Presentation 3: Bijon Chatterji, Biocrates

From Fair to FAIRness - A solution connecting Mx data from population-based studies globally

Poster pitches

Session chair: Justin van der Hooft 

Poster pitch 1: Merys Valdez

Predicting pulmonary embolism in COVID-19 patients located in the ICU; metabolomic prognostic biomarker

Poster pitch 2: Niek de Jonge

Fast and Reliable Machine-Learning supported Mass Spectral Library Querying with MS2Query

Poster pitch 3: Pablo Vangeenderhuysen

Integrating gut metabolomics and microbiomics towards biomarker discovery in pediatric cow’s milk allergy

Poster pitch 4: Anaïs Draguet

Evaluation of metabolic perturbations induced by ABCB5 in mice thanks to an 1H-NMR approach

Lunch break, posters, stands

Environmental Metabolomics

Session chair: Adriana Carvalho de Souza

Roel Vermeulen, University Utrecht

Exposome: big science where biology meets chemistry

Presentation 1: Yupeng He

Fast, online three-phase electroextraction for the analysis of trace-level basic and acidic pharmaceuticals in biofluids

Presentation 2: Mengmeng Xu

Using comprehensive lipid profiling to study effects of PFHxS during different stages of early zebrafish development 

Presentation 3: Tom Cools

Untargeted metabolomics reveals discriminative metabolic fingerprints in pregnant versus pseudo-pregnant giant pandas during the luteal phase

Coffee break

Biomedical applications 

Session chair: Celia Berkers 

Riekelt Houtkooper, Amsterdam UMC

NAD⁺ as a target to promote healthy aging

Presentation 1: Alessio Ciurli 

Temporally and spatially resolved metabolomic profiling of saliva

Presentation 2: Kathleen Wijnant

Determining the drivers of paediatric obesity in a deeply phenotyped cohort: how do diet, lifestyle, psychological stress and the salivary microbiome correlate to the salivary metabolome?

Keynote: Rick Dunn, University of Liverpool

Session chair: Celia Berkers - boardmember NMC

Understanding metabolism in human diseases – metabolomics and precision medicine

Closing