Keynote speakers

 

Our confirmed keynote speakers:

 

Alexander van Oudenaarden

Prof. dr. ir. Alexander van Oudenaarden

Hubrecht Institute-KNAW, University Medical Center Utrecht & Utrecht University

Prof. dr. ir. Alexander van Oudenaarden is director and group leader at the Hubrecht Institute (KNAW) and professor of quantitative biology of gene regulation at the Faculty of Science and the Faculty of Medicine at Utrecht University. His research group works with advanced (light) microscopy and sequencing technologies in order to study individual cells. Van Oudenaarden studied materials science and physics at Delft, where he also obtained his PhD in solid state physics. As a postdoc he worked at Stanford University collaborating with Steven Boxer and Julie Theriot. He was professor of physics and biology at the Massachusetts Institute of Technology (MIT). In 2012 he moved to the Hubrecht Institute after 15 years in the USA. His group combines techniques – in part developed by themselves – from developmental biology, molecular biology, physics, mathematics and computer science. He was awarded the 2011 and 2016 ERC Advanced Investigator grant and in 2017 van Oudenaarden won the Spinoza Award.

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Martin Kircher

Dr Martin Kircher
Junior Group Leader 'Computational Genome Biology’
Berlin Institute of Health

Dr. Martin Kircher joined BIH in March 2017 as a new Junior Research Group (JRG) Leader in the field of Bioinformatics. He describes the work of his "Computational Genome Biology" group and experience in a brief portrait.

The research of his group focuses on computational approaches of identifying functionally relevant genetic changes in disease and adaptation as well as developing more sensitive methods in diagnostics (especially exome, genome and cell-free DNA sequencing). Generally, our research spans the fields of sequence analysis, data mining, machine learning and functional genomics.

Based on a broad interest in genetics, epigenetics, and human adaptation, the group develops computational solutions to overcome technical and experimental obstacles in high-throughput sequencing-based protocols. The main focus area are computational approaches for identifying functionally relevant genetic.

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Jason Locasale

Jason Locasale
Assistant Professor of Pharmacology & Cancer Biology
Duke University

Jason W. Locasale, Ph.D. is a faculty member at Duke University in the School of Medicine. He graduated from Rutgers University, Summa Cum Laude with degrees in Chemistry and Physics. He received his Ph.D. at the Massachusetts Institute of Technology in Biological Engineering under the mentorship of Arup Chakraborty. He then conducted postdoctoral training Harvard Medical School under the guidance of Lewis Cantley as an American Cancer Society postdoctoral fellow and later as an Instructor on the faculty in the Department of Medicine.

Dr. Locasale has pioneered the use of metabolomics approaches to study cancer biology and metabolism.  He has made seminal contributions to our understanding of metabolism including the role of serine synthesis in cancers, defining the quantitative, mechanistic principles of the Warburg Effect and altered glucose metabolism in cancer, and the role of metabolism in mediating chromatin status and epigenetics.  His research combines quantitative approaches in metabolomics and mathematical modeling with biochemistry, cell biology and genetics.

Dr. Locasale is a recipient of the NIH Pathway to Indepence Award, the Benjamin Trump Award for Excellence in Cancer Research, and the American Cancer Society Research Scholar Award.  Dr. Locasale currently serves on the editorial board of PLoS Biology and has numerous advisory roles for industry, the NIH common fund, and the National Cancer Institute.  His laboratory is funded primarily by NIH.  He has authored over 100 publications and numerous textbooks chapters and patents.

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Chiara Dalla Man

Chiara Dalla Man
Associate professor in Bioengineering
University of Padova, Department of Information Engineering

Chiara Dalla Man was born in Venice, Italy, on March 2, 1977. She graduated cum laude in Electronics Engineering at the University of Padova in 2000 and received the Ph.D degree in Biomedical Engineering from the University of Padova and City University London, in 2005. She is currently Associate Professor in Bioengineering at University of Padova. Her research activity, carried out in collaboration with Italian and foreign investigators, regards mainly mathematical modeling of physiological systems, in particular metabolic and endocrine systems. She is author of more than one hundred publications (Scopus reports 114 papers in the period 2002-2018, quoted 5626 times, with an h-index of 37) on international journals and 4 International Patents. She is on the editorial board of Journal of Diabetes Science and Technology and Frontiers in Systems Biology and serves as reviewer for several peer reviewed journal in the field.

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